The Thiruvananthapuram to Dharmapuri (Tamil Nadu) bus route covers approximately 551 kms and takes about 10 hrs 46 mins. A total of 47 direct buses operated by 21 bus operators run on this route. The first bus departs at 07:00, and the last bus leaves at 22:35.
Major boarding points in Thiruvananthapuram include Aristo Junction, Attingal, Balaramapuram, Chakka Pass, East Thampanoor, Fortis Hospital Cunningham Road, Infosys Campus, Kaliyakavilai, Kaniyapuram,, Kazhakootam, while common drop locations in Dharmapuri (Tamil Nadu) are Ammapet Bypass Road.
RTC and private operators such as Kallada Travels (Suresh Kallada), JaiSai Roadlinks (JSR), Punchiry Travels and Holidays offer Volvo, AC, and non-AC seater and sleeper buses. Ticket prices on redBus range from INR 1900 - INR 5981.00 depending on the bus type and features.



