The Thiruvananthapuram to Ernakulam bus route covers approximately 218 kms and takes about 5 hrs 27 mins. A total of 176 direct buses operated by 24 bus operators run on this route. The first bus departs at 00:00, and the last bus leaves at 23:45.
Major boarding points in Thiruvananthapuram include Aristo Junction, Attingal, Balaramapuram, Chakka Pass, East Thampanoor, Fortis Hospital Cunningham Road, Infosys Campus, Kaniyapuram,, Kazhakootam, Kesavadasapuram, while common drop locations in Ernakulam are Athani (Ekm), Chottanikkara, Edapally, KSRTC Bus Stand, Kadavanthara, Kalamassery, MG Road, Others, Palarivattom, Paravoor Kavala.
RTC and private operators such as Kallada Travels (Suresh Kallada), JaiSai Roadlinks (JSR), A1 Travels , Surya Connect, EMERALD TRAVELS offer Volvo, AC, and non-AC seater and sleeper buses. Ticket prices on redBus range from INR 280 - INR 2098.00 depending on the bus type and features.



