The Thiruvananthapuram to Vyttila bus route covers approximately 214 kms and takes about 4 hrs 12 mins. A total of 9 direct buses operated by 4 bus operators run on this route. The first bus departs at 19:30, and the last bus leaves at 21:40.
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Major boarding points in Thiruvananthapuram include Aristo Junction, Attingal, Balaramapuram, East Thampanoor, Kaniyapuram,, Kazhakootam, Kesavadasapuram, Others, Pattam, Sreekaryam, while common drop locations in Vyttila are KSRTC Bus Stand, Kaloor, Vyttila.
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RTC and private operators such as Madhavi Travels offer Volvo, AC, and non-AC seater and sleeper buses. Ticket prices on redBus range from INR 499 - INR 1150.00 depending on the bus type and features.



