The Thiruvananthapuram to Payyoli bus route covers approximately 425 kms and takes about 9 hrs 27 mins. A total of 3 direct buses operated by 3 bus operators run on this route. The first bus departs at 19:00, and the last bus leaves at 20:00.
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Major boarding points in Thiruvananthapuram include Aristo Junction, Attingal, Infosys Campus, Kaniyapuram,, Kazhakootam, Kesavadasapuram, Others, Pattam, Sreekaryam, Techno Park, while common drop locations in Payyoli are Payyoli.
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RTC and private operators such as EMERALD TRAVELS offer Volvo, AC, and non-AC seater and sleeper buses. Ticket prices on redBus range from INR 800 - INR 1200.00 depending on the bus type and features.



