The Salem to Thoothukudi bus route covers approximately 382 kms and takes about 6 hrs 10 mins. A total of 15 direct buses operated by 10 bus operators run on this route. The first bus departs at 00:05, and the last bus leaves at 23:55.
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Major boarding points in Salem include Andagalur Gate, Avr Roundana, Kondalampatti, Others, Salem New Bus Stand, Seelanaickenpatti, Thiruvagoundanur, while common drop locations in Thoothukudi are Ettaiyapuram Road, New Bus Stand, Old Bus Stand, Others.
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RTC and private operators such as Royal Travels, Royal Roadlinks, Sri SMS Travels, AAHHAA TOURIST, Thirumalaivasan Transports offer Volvo, AC, and non-AC seater and sleeper buses. Ticket prices on redBus range from INR 441 - INR 2000.00 depending on the bus type and features.



