The Salem to Pondicherry bus route covers approximately 215 kms and takes about 4 hrs 24 mins. A total of 49 direct buses operated by 23 bus operators run on this route. The first bus departs at 00:15, and the last bus leaves at 23:59.
Major boarding points in Salem include Avr Roundana, Ayodhiyapatinam, Kondalampatti, Mettupatti, Mettupatti Toll Gate, Others, Salem New Bus Stand, Sankagiri, Seelanaickenpatti, Valappadi, while common drop locations in Pondicherry are Ariyankuppam, Avm College, Indira Gandhi Statue, Jipmer, Kalapet, Kalapet University, Mvm College, New Bus Stand, Others, Rajiv Gandhi Statue.
RTC and private operators such as Kallada Travels (Suresh Kallada), Kalaimakal Travelss, Krish Travels, Vetri Travels, Surya Connect offer Volvo, AC, and non-AC seater and sleeper buses. Ticket prices on redBus range from INR 376 - INR 2066.00 depending on the bus type and features.



