The Perinthalmanna to Salem bus route covers approximately 273 kms and takes about 5 hrs 36 mins. A total of 9 direct buses operated by 8 bus operators run on this route. The first bus departs at 19:00, and the last bus leaves at 22:00.
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Major boarding points in Perinthalmanna include Angadipuram, Perinthalamanna, Perinthalmanna, while common drop locations in Salem are Avr Roundana, Kondalampatti, Salem New Bus Stand, Seelanaickenpatti, Vinayaka Mission University.
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RTC and private operators such as YBM Travels(BLM), Tippusultan Travels offer Volvo, AC, and non-AC seater and sleeper buses. Ticket prices on redBus range from INR 424 - INR 1903.00 depending on the bus type and features.



