The Nagpur to Khandwa bus route covers approximately 359 kms and takes about 9 hrs 23 mins. A total of 4 direct buses operated by 4 bus operators run on this route. The first bus departs at 18:00, and the last bus leaves at 18:30.
Major boarding points in Nagpur include Ashirwad Theatre, Dhantoli, Others, Wadi, while common drop locations in Khandwa are Bus stand, Khandwa Geet Travels Bus Stand, New Bus Stand.
RTC and private operators such as RoyalStar Bus Amt offer Volvo, AC, and non-AC seater and sleeper buses. Ticket prices on redBus range from INR 951 - INR 5000.00 depending on the bus type and features.



