The Mannuthy to Salem bus route covers approximately 290 kms and takes about 4 hrs 31 mins. A total of 35 direct buses operated by 21 bus operators run on this route. The first bus departs at 11:31, and the last bus leaves at 23:56.
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Major boarding points in Mannuthy include Kadavanthara, Manuthy Pass, while common drop locations in Salem are Avr Roundana, Kondalampatti, Mettupatti, Peramanur, Salem New Bus Stand, Sankagiri, Seelanaickenpatti, Valappadi, Vinayaka Mission University.
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RTC and private operators such as Surya Connect, Diya Bus, Kalyani Travels offer Volvo, AC, and non-AC seater and sleeper buses. Ticket prices on redBus range from INR 486 - INR 2700.00 depending on the bus type and features.



