The Mulki to Thiruvananthapuram bus route covers approximately 643 kms and takes about 16 hrs 3 mins. A total of 4 direct buses operated by 2 bus operators run on this route. The first bus departs at 17:25, and the last bus leaves at 17:25.
Major boarding points in Mulki include MULKI, while common drop locations in Thiruvananthapuram are Attingal, Chakka Pass, Infosys Campus, Kaniyapuram,, Kazhakootam, Techno Park, Thampanoor.
RTC and private operators such as Kohinoor Travels offer Volvo, AC, and non-AC seater and sleeper buses. Ticket prices on redBus range from INR 1000 - INR 4999.00 depending on the bus type and features.



