The Mandsaur to Nagpur bus route covers approximately 678 kms and takes about 22 hrs 41 mins. A total of 5 direct buses operated by 5 bus operators run on this route. The first bus departs at 02:10, and the last bus leaves at 23:59.
Major boarding points in Mandsaur include Bpl Circle Mandsaur, Maharana Pratap Bus Stand, while common drop locations in Nagpur are Ashirwad Theatre, Butibori, Chatrapathi, Ganesh Pet, Others, S T Bus Stand.
RTC and private operators such as M R Travels offer Volvo, AC, and non-AC seater and sleeper buses. Ticket prices on redBus range from INR 1428 - INR 4850.00 depending on the bus type and features.



