The Chennai to Kayamkulam bus route covers approximately 733 kms and takes about 13 hrs 30 mins. A total of 1 direct buses operated by 1 bus operators run on this route. The first bus departs at 19:15, and the last bus leaves at 19:15.
Major boarding points in Chennai include Chengalpattu, Guduvancheri, Koyambedu, Maduravoyal, Mahendra City, Maraimalai Nagar, Melmaruvathur, Perungalathur, Porur, SRM University, while common drop locations in Kayamkulam are Chengalpattu, Guduvancheri, Koyambedu, Maduravoyal, Mahendra City, Maraimalai Nagar, Melmaruvathur, Perungalathur, Porur, SRM University.
RTC and private operators such as Azul Transports Private Limited offer Volvo, AC, and non-AC seater and sleeper buses. Ticket prices on redBus range from INR 1850 - INR 1750 depending on the bus type and features.



