The Pathanamthitta to Calicut bus route covers approximately 309 kms and takes about 0 hrs 0 mins. A total of 4 direct buses operated by 1 bus operators run on this route. The first bus departs at , and the last bus leaves at .
Major boarding points in Pathanamthitta include CHANGANASSERY BUS STOP, KOZHENJERY, KUMBANAD, PATHANAMTHITTA, THIRUVALLA BUS STOP, while common drop locations in Calicut are KOZHIKODE.
RTC and private operators such as KSRTC (Kerala) offer Volvo, AC, and non-AC seater and sleeper buses. Ticket prices on redBus range from - depending on the bus type and features.



