The Hosur to Tirunelveli bus route covers approximately 523 kms and takes about 8 hrs 28 mins. A total of 65 direct buses operated by 33 bus operators run on this route. The first bus departs at 00:30, and the last bus leaves at 23:15.
Major boarding points in Hosur include Bus Stand, Others, while common drop locations in Tirunelveli are Junction Old Bus Stand, KTC Nagar, Kayathar, Papanasam, Sankarnagar, Thatchanallur, Tirunelveli bypass, Udayarpatti, Vannarpettai.
RTC and private operators such as Kallada Travels (Suresh Kallada), MRM Travels, SRS Travels, Punchiry Travels and Holidays, IntrCity SmartBus offer Volvo, AC, and non-AC seater and sleeper buses. Ticket prices on redBus range from INR 649 - INR 4195.00 depending on the bus type and features.



