The Palladam to Tirunelveli bus route covers approximately 310 kms and takes about 6 hrs 3 mins. A total of 30 direct buses operated by 21 bus operators run on this route. The first bus departs at 13:10, and the last bus leaves at 23:59.
Major boarding points in Palladam include Palladam, Sulur, while common drop locations in Tirunelveli are KTC Nagar, Kayathar, Others, Papanasam, Passport Seva Kendra, Sankarnagar, Thatchanallur, Tirunelveli bypass, Udayarpatti, Vannarpettai.
RTC and private operators such as Jai Vishnu Travels, Sri Selvam Travels (PSP), PSS Transport, SPS Travels India, KNT Travels offer Volvo, AC, and non-AC seater and sleeper buses. Ticket prices on redBus range from INR 349 - INR 3499.00 depending on the bus type and features.



