The Koyambedu to Shanthinagar bus route covers approximately 324 kms and takes about 0 hrs 30 mins. A total of 260 direct buses operated by 39 bus operators run on this route. The first bus departs at , and the last bus leaves at .
Major boarding points in Koyambedu include Adyar, ashok pillar, Chennai Central Railway Station, Egmore, Ekkatuthangal, Guindy, kanchipuram bypass, Kandanchavadi, Karappakkam, KasiTheatre, while common drop locations in Shanthinagar are Shanthi Nagar Bus Stand, Attibele, BOMMASANDRA, Dairy circle, Electronic City Toll Gate, KALASIPALAYAM BUS STAND, Madiwala Police Station, Majestic, SHANTHINAGAR BMTC BUS STAND(DOUBLE ROAD), shanthinagar BMTC bus stand(Double Road).
RTC and private operators such as TNSTC, National Travels, Bharathi Travels , National travels chn, Green Line Travels offer Volvo, AC, and non-AC seater and sleeper buses. Ticket prices on redBus range from INR 300 - depending on the bus type and features.



